Spectral matching technology for light-emitting diode-based jaundice photodynamic therapy device

The objective of this paper is to obtain the spectrum of light-emitting diode (LED)-based jaundice photodynamic therapy
device (JPTD), the bilirubin absorption spectrum in vivo was regarded as target spectrum. According to the spectral
constructing theory, a simple genetic algorithm as the spectral matching algorithm was first proposed in this study. The
optimal combination ratios of LEDs were obtained, and the required LEDs number was then calculated. Meanwhile, the
algorithm was compared with the existing spectral matching algorithms. The results show that this algorithm runs faster
with higher efficiency, the switching time consumed is 2.06 s, and the fitting spectrum is very similar to the target
spectrum with 98.15% matching degree. Thus, blue LED-based JPTD can replace traditional blue fluorescent tube, the
spectral matching technology that has been put forward can be applied to the light source spectral matching for jaundice
photodynamic therapy and other medical phototherapyless